Mice deprived of the ability to synthesize PTP1B, acquired sverhchuvstvitelnost ь to insulinu and leptinu, resulting in accelerated metabolism of animals. It will be recalled that the thick of people is too many leptina. In normal, the hormone reduces appetite, but pereedanii body gradually loses sensitivity to gormonu. Likewise, by moving insensitive to insulinu if you type two diabetes. To date, generally great social significance BAD both prevention and treatment of most of the so-called diseases of civilization, the ale which is primarily concerned with irregularities in the food status of modern man. These violations, and caused their disease are well known. Excess intake of simple carbohydrates and saturated fats with the express deficit vitamins, minerals and fibre in the diet, vegetable fats and many other micronutrient explains pandemic of cardiovascular deaths and cancer, diabetes, obesity, etc. Immunodefitsitnye and allergic condition diseases of the connective tissue and the gastrointestinal tract is also very much a product of poor nutrition. Do I have to say that the total public health indutsirovannymi poor diet disease is enormous mediko-ekonomicheskie costs of low availability, high morbidity and mortality of early beta. Faceless figures for many medical statistics actually mean millions of personal tragedies. Academic Medicine, reaching tremendous strides in the treatment of acute illnesses, proved ineffective, if not powerless in the prevention and treatment of chronic diseases. Long-term drug therapy of chronic diseases often fraught with side effects and the development of tolerance, in addition, it originally had a number of contraindications.