Predraspolagayuschee value can be congenital and acquired deficiency of neuroendocrine regulation of coping reactions (hypoxia, infection, intoxication wasted in antenatalnom period, hereditary factors, etc.); Cardiovascular diseases (hypertension, rheumatic heart disease); Disruption of the endocrine glands (diabetes, Ray); Kidneys (nephritis, medicine); Hepatobiliar System (hepatitis, holetsistit); metabolism (obesity); expressed stressful situations; intoxication (smoking, etc.); allergic and immunologic reactions. So etiology gestosis definitively determined, there are currently over 30 different theories. However, the definition of gestosis, such as disease adaptation, the most responsible way of thinking about it. Recent studies suggest that the main etiologicheskim factor is the failure mechanisms to adapt to emerging pregnancy. It is known that almost all systems are pregnant organism physiological changes to the normal course of the pregnancy and the proper development of the foetus. The development of these changes with prisposobitelny nature is governed by the nervous system, with the active participation of hormones produced by glands Endocrine and platsente. Epidemiology Despite extensive research, the problem gestosis (eclampsia, hypertension induced by pregnancy) remains valid. Frequency of them is 8-16%. They are 2-3 in the maternal mortality rate is both a major cause of adverse perinatal outcomes. Frequency HELLP-sindroma in perinatal centers is 1 to 150-300 deliveries. The maternal mortality rate has reached 3.5%, and perinatal 79%. Risk groups : 1. Women with chronic stress, fatigue, reflecting the sluggishness of central nervous system and weak adaptation ability.
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